PBPK modeling to predict the pharmacokinetics of venlafaxine and its active metabolite in different CYP2D6 genotypes and drug–drug interactions with clarithromycin and paroxetine-Reference-Cited by-同舟云学术

PBPK modeling to predict the pharmacokinetics of venlafaxine and its active metabolite in different CYP2D6 genotypes and drug–drug interactions with clarithromycin and paroxetine

Published:2024-04-25 Issue:5 Volume:47 Page:481-504
ISSN:0253-6269
Container-title:Archives of Pharmacal Research
language:en
Short-container-title:Arch. Pharm. Res.

Author:

Cho Chang-Keun,Kang Pureum,Jang Choon-Gon,Lee Seok-Yong^ORCID,Lee Yun Jeong,Bae Jung-Woo,Choi Chang-Ik

Funder

National Research Foundation of Korea

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1007/s12272-024-01495-0.pdf

Reference107 articles.

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3. Bachmeier CJ, Beaulieu-Abdelahad D, Ganey NJ, Mullan MJ, Levin GM (2011) Induction of drug efflux protein expression by venlafaxine but not desvenlafaxine. Biopharm Drug Dispos 32(4):233–244. https://doi.org/10.1002/bdd.753

4. Bae JW, Oh KY, Yoon SJ, Shin HB, Jung EH, Cho CK, Lim CW, Kang P, Choi CI, Jang CG, Lee SY, Lee YJ (2020) Effects of CYP2D6 genetic polymorphism on the pharmacokinetics of metoclopramide. Arch Pharm Res 43(11):1207–1213. https://doi.org/10.1007/s12272-020-01293-4

5. Ball SE, Ahern D, Scatina J, Kao J (1997) Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2. Br J Clin Pharmacol 43(6):619–626. https://doi.org/10.1046/j.1365-2125.1997.00591.x

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