Biotherapeutic protein formulation variables influence protein integrity and can promote post-translational modifications as shown using chicken egg white lysozyme as a model system-Reference-Cited by-同舟云学术

Biotherapeutic protein formulation variables influence protein integrity and can promote post-translational modifications as shown using chicken egg white lysozyme as a model system

Published:2015-12-23 Issue:4 Volume:38 Page:589-596
ISSN:0141-5492
Container-title:Biotechnology Letters
language:en
Short-container-title:Biotechnol Lett

Author:

Gourbatsi Evdoxia,Povey Jane,Uddin Shahid,Smales C. Mark

Funder

BBSRC

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Biotechnology,Bioengineering,Applied Microbiology and Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s10529-015-2014-y.pdf

Reference14 articles.

1. Chaudhuri R, Cheng Y, Middaugh CR, Volkin DB (2014) High-throughput biophysical analysis of protein therapeutics to examine interrelationships between aggregate formation and conformational stability. AAPS J 16:48–64

2. Domart-Coulon I, Doumenc D, Auzoux-Bordenave S, Le Fichant Y (1994) Identification of media supplements that improve the viability of primarily cell cultures of Crassostrea gigas oysters. Cytotechnol 16:109–120

3. Lu Y, Harding SE, Rowe AJ, Davis KG, Fish B, Varley P, Gee C, Mulot S (2008) The effect of a point mutation on the stability of IgG4 as monitored by analytical ultracentrifugation. J Pharm Sci 97:960–969

4. Mitragotri S, Burke PA, Langer R (2014) Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies. Nat Rev Drug Discov 13:655–672

5. Povey JF, Smales CM, Hassard SJ, Howard MJ (2007) Comparison of the effects of 2,2,2-trifluoroethanol on peptide and protein structure and function. J Struct Biol 157:329–338

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Aggregation Time Machine: A Platform for the Prediction and Optimization of Long-Term Antibody Stability Using Short-Term Kinetic Analysis;Journal of Medicinal Chemistry;2022-01-28

2. Investigating the Influence of Polysorbate 20/80 and Polaxomer P188 on the Surface & Interfacial Properties of Bovine Serum Albumin and Lysozyme;Pharmaceutical Research;2019-05-20

3. The effect of formulation variables on protein stability and integrity of a model IgG4 monoclonal antibody and translation to formulation of a model ScFv;Biotechnology Letters;2017-09-23

4. Investigations into, and development of, a lyophilized and formulated recombinant human factor IX produced from CHO cells;Biotechnology Letters;2017-05-08