Engineering CHO cells galactose metabolism to reduce lactate synthesis
Author:
Funder
CONICYT
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Biotechnology,Bioengineering,Applied Microbiology and Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/s10529-019-02680-8.pdf
Reference21 articles.
1. Altamirano Claudia, Illanes Andres, Becerra Silvana, Cairó Jordi Joan, Gòdia Francesc (2006) Considerations on the lactate consumption by CHO cells in the presence of galactose. J Biotechnol 125(4):547–556. https://doi.org/10.1016/j.jbiotec.2006.03.023
2. Altamirano Claudia, Berrios Julio, Vergara Mauricio, Becerra Silvana (2013) Advances in improving mammalian cells metabolism for recombinant protein production. Electron J Biotechnol 16(3):10. https://doi.org/10.2225/vol16-issue3-fulltext-2
3. Bahr Scott M, Borgschulte Trissa, Kayser Kevin J, Lin Nan (2009) Using microarray technology to select housekeeping genes in Chinese hamster ovary cells. Biotechnol Bioeng 104(5):1041–1046. https://doi.org/10.1002/bit.22452
4. Chen K, Liu Q, Xie L, Sharp PA, Wang DI (2001) Engineering of a mammalian cell line for reduction of lactate formation and high monoclonal antibody production. Biotechnol Bioeng 72(1):55–61
5. Gambhir Anshu, Korke Rashmi, Lee Jongchan, Peng-Cheng Fu, Europa Anna, Wei-Shou Hu (2003) Analysis of cellular metabolism of hybridoma cells at distinct physiological states. J Biosci Bioeng 95(4):317–327. https://doi.org/10.1016/S1389-1723(03)80062-2
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