Identifying modifier genes of monogenic disease: strategies and difficulties
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics
Link
http://link.springer.com/content/pdf/10.1007/s00439-008-0560-2.pdf
Reference72 articles.
1. Abecasis GR, Cardon LR, Cookson WO (2000) A general test of association for quantitative traits in nuclear families. Am J Hum Genet 66:279–292
2. Antonarakis S, Beckmann J (2006) Mendelian disorders deserve more attention. Nat Rev Genet 7:277–282
3. Beaumont V, Jacotot B, Beaumont JL (1976) Ischaemic disease in men and women with familial hypercholesterolaemia and xanthomatosis: a comparative study of genetic and environmental factors in 274 heterozygous cases. Atherosclerosis 24:441–450
4. Beckmann JS, Estivill X, Antonarakis SE (2007) Copy number variants and genetic traits: closer to the resolution of phenotypic to genotypic variability. Nat Rev Genet 8:639–646
5. Blackman S, Deering-Brose R, McWilliams R, Naughton K, Coleman B, Lai T, Algire M, Beck S, Hoover-Fong J, Hamosh A, Fallin M, West K, Arking D, Chakravarti A, Cutler D, Cutting G (2006) Relative contribution of genetic and nongenetic modifiers to intestinal obstruction in cystic fibrosis. Gastroenterology 131:1030–1039
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