Effect of Vitreoscilla Hemoglobin and Culture Conditions on Production of Bacterial l-Asparaginase, an Oncolytic Enzyme

Author:

Erenler Sebnem O.,Geckil Hikmet

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Applied Microbiology and Biotechnology,Biochemistry,General Medicine,Bioengineering,Biotechnology

Reference43 articles.

1. Ettinger, L. J., Ettinger, A. G., Avramis, V. I., & Gaynon, P. S. (1997). Acute lymphoblastic leukaemia: a guide to asparaginase and pegaspargase therapy. Biodrugs, 7, 30–39.

2. Geckil, H., & Gencer, S. (2004). Production of l-asparaginase in Enterobacter aerogenes expressing Vitreoscilla hemoglobin for efficient oxygen uptake. Applied Microbiology and Biotechnology, 63, 691–697.

3. Mukherjee, J., Majumdar, S., & Scheper, T. (2000). Studies on nutritional and oxygen requirements for production of l-asparaginase by Enterobacter aerogenes. Applied Microbiology and Biotechnology, 53, 180–184.

4. Lee, S. M., Ross, J. T., Gustafson, M. E., Wroble, M. H., & Muschik, G. M. (1986). Large-scale recovery and purification of l-asparaginase from Erwinia carotovora. Applied Microbiology and Biotechnology, 12, 229–247.

5. Cornea, C. P., Lupescu, I., Vatafu, I., Savoiu, V. G., & Campeanu, G. H. (2000). Isolation and characterization of some L-asparaginase producing recombinant Escherichia coli strains. Roumamian Biotechnological Letters, 5, 471–478.

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