Quantitative Systems Pharmacology: A Framework for Context
Author:
Funder
National Institutes of Health
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,Genetics,Biochemistry
Link
http://link.springer.com/content/pdf/10.1007/s40495-016-0058-x.pdf
Reference124 articles.
1. Aarons L. Physiologically based pharmacokinetic modelling: a sound mechanistic basis is needed. Br J Clin Pharmacol. 2005;60(6):581–3. doi: 10.1111/j.1365-2125.2005.02560.x .
2. Alesci S, Martinez PE, Kelkar S, Ilias I, Ronsaville DS, Listwak SJ, et al. Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion: clinical implications. J Clin Endocrinol Metab. 2005;90(5):2522–30. doi: 10.1210/jc.2004-1667 .
3. Allan G, Davis J, Dickins M, Gardner I, Jenkins T, Jones H, et al. Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man. Xenobiotica. 2008;38(6):620–40. doi: 10.1080/00498250802069088 .
4. Androulakis IP. Systems engineering meets quantitative systems pharmacology: from low-level targets to engaging the host defenses. Wiley Interdiscip Rev Syst Biol Med. 2015;7(3):101–12. doi: 10.1002/wsbm.1294 .
5. Androulakis IP, Kamisoglu K, Mattick JS. Topology and dynamics of signaling networks: in search of transcriptional control of the inflammatory response. Annu Rev Biomed Eng. 2013;15:1–28. doi: 10.1146/annurev-bioeng-071812-152425 .
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