Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man-Reference-Cited by-同舟云学术

Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man

Published:2008-06-01 Issue:6 Volume:38 Page:620-640
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Allan G.¹,Davis J.¹,Dickins M.¹,Gardner I.¹,Jenkins T.²,Jones H.¹,Webster R.¹,Westgate H.¹

Affiliation:

1. Clinical Pharmacology, Pharmacokinetics, Dynamics and Metabolism , Sandwich, UK

2. Clinical Research, Pfizer Global Research and Development , Sandwich, UK

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498250802069088

Reference26 articles.

1. Predicting the impact of physiological and biochemical processes on oral drug bioavailability

2. Cross-Resistance among Nonnucleoside Reverse Transcriptase Inhibitors Limits Recycling Efavirenz after Nevirapine Failure

3. Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: Extrapolation of data to benzodiazepines and phenytoin

4. Physiological Parameter Values for Physiologically Based Pharmacokinetic Models

5. Adverse effects of antiretroviral therapy

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