Mechanism of action of HI-6 on soman inhibition of acetylcholinesterase in preparations of rat and human skeletal muscle; comparison to SAD-128 and PAM-2-Reference-Cited by-同舟云学术

Mechanism of action of HI-6 on soman inhibition of acetylcholinesterase in preparations of rat and human skeletal muscle; comparison to SAD-128 and PAM-2

Published:1989-02 Issue:1 Volume:63 Page:68-71
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Grubič Zoran,Tomažič Anton

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/BF00334637.pdf

Reference15 articles.

1. Clement JG (1981) Toxicology and pharmacology of bispyridinium oximes — insight into the mechanism of action of soman poisoning in vivo. Fundam Appl Toxicol 1: 193–202

2. De Jong LPA, Wolring GZ (1980) Reactivation of acetylcholinesterase inhibited by 1,2,2-trimethylpropylmethyl phosphonofluoridate (soman) with HI-6 and related oximes. Biochem Pharmacol 29: 2379–2387

3. De Jong LPA, Wolring GZ (1984) Stereospecific reactivation by some Hagedorn-oximes of acetylcholinesterase from various species including man, inhibited by soman. Biochem Pharmacol 33: 1119–1125

4. Grubič Z, Sketelj J, Klinar B, Brzin M (1981) Recovery of acetylcholinesterase in the diaphragm, brain and plasma of the rat after irreversible inhibition by soman: a study of cytochemical localization and molecular forms of the enzyme in the motor end plate. J Neurochem 37: 909–916

5. Harris LW, Heyl WC, Stitcher DL, Broomfield CA (1978) Effects of 1,1′-oxydimethylene bis-(4- tert-butylpyridinium chloride) (SAD-128) and decamethonium on reactivation of soman and sarin-inhibited cholinesterase by oximes. Biochem Pharmacol 27: 757–761

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