RUNX3 improves CAR-T cell phenotype and reduces cytokine release while maintaining CAR-T function
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Hematology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s12032-022-01913-7.pdf
Reference39 articles.
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2. Marofi F, Rahman HS, Al-Obaidi ZMJ, Jalil AT, Abdelbasset WK, Suksatan W, et al. Novel CAR T therapy is a ray of hope in the treatment of seriously ill AML patients[J]. Stem Cell Res Ther. 2021;12(1):465.
3. Scarfo I, Maus MV. Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment[J]. J Immunother Cancer. 2017;5:28.
4. Kyte JA. Strategies for improving the efficacy of CAR T cells in solid cancers[J]. Cancers. 2022;14(3):571.
5. Wang Z, Han W. Biomarkers of cytokine release syndrome and neurotoxicity related to CAR-T cell therapy[J]. Biomarker Res. 2018;6:4.
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