CDK2-instigates C/EBPα degradation through SKP2 in Acute myeloid leukemia
Author:
Funder
Lady Tata Memorial Trust
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Hematology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s12032-021-01523-9.pdf
Reference31 articles.
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2. Min YM, Zhang H, Giovanni AG, Henry YH, Staber PB, Zhang P, Levantini E, Alberich-Jordà M, Zhang J, Kawasaki A, Tenen DG. C/EBPa controls acquisition and maintenance of adult hematopoietic stem cell quiescence. Nat Cell Biol. 2013;15:385–94.
3. Pal P, Lochab S, Kanaujiya JK, Kapoor I, Sanyal S, Behre G, Trivedi AK. E6AP, an E3 ubiquitin ligase negatively regulates granulopoiesis by targeting transcription factor C/EBPalpha for ubiquitin-mediated proteasome degradation. Cell Death Dis. 2013;4:e590.
4. Avellino R, Delwel R. Expression and regulation of C/EBPalpha in normal myelopoiesis and in malignant transformation. Blood. 2017;129:2083–91.
5. Pulikkan JA, Tenen DG, Behre G. C/EBPalpha deregulation as a paradigm for leukemogenesis. Leukemia. 2017;31:2279–85.
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