The impact of P-gp functionality on non-steady state relationships between CSF and brain extracellular fluid
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
http://link.springer.com/content/pdf/10.1007/s10928-013-9314-4.pdf
Reference80 articles.
1. De Lange ECM, de Boer AG, Breimer DD (2000) Methodological issues in microdialysis sampling for pharmacokinetic studies. Adv Drug Del Rev 45:125–148
2. Hammarlund-Udenaes M (2009) Active-site concentrations of chemicals—are they a better predictor of effect than plasma/organ/tissue concentrations? Basic Clin Pharmacol Toxicol 106:215–220
3. De Lange ECM, Danhof M, de Boer AG, Breimer DD (1997) Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood–brain barrier. Brain Res Rev 25:27–49
4. Hammarlund-Udenaes M, Bredberg U, Fridén M (2009) Methodologies to assess brain drug delivery in lead optimization. Curr Top Med Chem 9:148–162
5. Westerhout J, Danhof M, de Lange ECM (2011) Preclinical prediction of human brain target site concentrations: considerations in extrapolating to the clinical setting. J Pharm Sci 100:3577–3593
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