A tutorial on model informed approaches to cardiovascular safety with focus on cardiac repolarisation
Author:
Funder
Marie Curie FP7 ITN EID project
Innovative Medicines Initiative (IMI) Joint Undertaking
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
http://link.springer.com/article/10.1007/s10928-018-9589-6/fulltext.html
Reference79 articles.
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3. Stone JA, Banfield C, Pfister M, Tannenbaum S, Allerheiligen S, Wetherington JD, Krishna R, Grasela DM (2010) Model-based drug development survey finds pharmacometrics impacting decision making in the pharmaceutical industry. J Clin Pharmacol 50(9 Suppl):20s–30s. https://doi.org/10.1177/0091270010377628
4. Wetherington JD, Pfister M, Banfield C, Stone JA, Krishna R, Allerheiligen S, Grasela DM (2010) Model-based drug development: strengths, weaknesses, opportunities, and threats for broad application of pharmacometrics in drug development. J Clin Pharmacol 50(9 Suppl):31s–46s. https://doi.org/10.1177/0091270010377629
5. Zhang L, Pfister M, Meibohm B (2008) Concepts and Challenges in Quantitative Pharmacology and Model-Based Drug Development. AAPS J 10(4):552–559. https://doi.org/10.1208/s12248-008-9062-3
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