Rare germline variants in the AXIN2 gene in families with colonic polyposis and colorectal cancer
Author:
Funder
National Health and Medical Research Council
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics(clinical),Oncology,Genetics
Link
https://link.springer.com/content/pdf/10.1007/s10689-021-00283-9.pdf
Reference30 articles.
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3. Powell SM, Zilz N, Beazer-Barclay Y et al (1992) APC mutations occur early during colorectal tumorigenesis. Nature 359(6392):235–7
4. Behrens J, Jerchow BA, Wurtele M et al (1998) Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science 280(5363):596–9
5. Jho EH, Zhang T, Domon C, Joo CK, Freund JN, Costantini F (2002) Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 22(4):1172–1183
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