Pharmacogenomic associations of cyclophosphamide pharmacokinetic candidate genes with 4hydroxycyclophosphamide formation in children with Cancer-Reference-Cited by-同舟云学术

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Pharmacogenomic associations of cyclophosphamide pharmacokinetic candidate genes with 4hydroxycyclophosphamide formation in children with Cancer

Published:2024-07-30 Issue: Volume: Page:
ISSN:0344-5704
Container-title:Cancer Chemotherapy and Pharmacology
language:en
Short-container-title:Cancer Chemother Pharmacol

Author:

Navarro Sandi L.,Pinto Navin,Hawkins Douglas S.,Park Julie R.,Dilmaghani Saam,Rimorin Christine,Wurscher Michelle,McCune Jeannine S.

Funder

National Institutes of Health

Children’s Foundation

Fraternal Order of Eagles - Auburn

Alex’s Lemonade Stand

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1007/s00280-024-04703-2.pdf

Reference21 articles.

1. 1. Raccor BS, Claessens AJ, Dinh JC, Park JR, Hawkins DS, Thomas SS, Makar KW, McCune JS, Totah RA (2012) Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo. Drug Metab Dispos 40 (1):54–63. doi:10.1124/dmd.111.039347

2. 2. Kalhorn TF, Howald WN, Cole S, Phillips B, Wang J, Slattery JT, McCune JS (2006) Rapid quantitation of cyclophosphamide metabolites in plasma by liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 835 (1–2):105–113

3. 3. de Jonge ME, Huitema AD, Rodenhuis S, Beijnen JH (2005) Clinical pharmacokinetics of cyclophosphamide. Clin Pharmacokinet 44 (11):1135–1164

4. 4. Pinto N, Navarro SL, Rimorin C, Wurscher M, Hawkins DS, McCune JS (2021) Pharmacogenomic associations of cyclophosphamide pharmacokinetic candidate genes with event-free survival in intermediate-risk rhabdomyosarcoma: A report from the Children’s Oncology Group. Pediatr Blood Cancer 68 (11):e29203. doi: 29210.21002/pbc.29203. doi:10.1002/pbc.29203

5. 5. Pinto N, Ludeman SM, Dolan ME (2009) Drug focus: Pharmacogenetic studies related to cyclophosphamide-based therapy. Pharmacogenomics 10 (12):1897–1903. doi:10.2217/pgs.09.134

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