Drug resistance to nelarabine in leukemia cell lines might be caused by reduced expression of deoxycytidine kinase through epigenetic mechanisms
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology
Link
https://link.springer.com/content/pdf/10.1007/s00280-021-04373-4.pdf
Reference18 articles.
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2. Asano T (2020) Drug resistance in cancer therapy and the possible role of epigenetics. J Nippon Med Sch 87:244–251. https://doi.org/10.1272/jnms.JNMS.2020_87-508
3. Yamanishi M, Narazaki H, Asano T (2015) Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase. Exp Hematol 43:207–214. https://doi.org/10.1016/j.exphem.2014.11.001
4. Homminga I, Zwaan CM, Manz CY, Parker C, Bantia S, Smits WK, Higginbotham F, Pieters R, Meijerink JP (2011) In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia. Blood 118:2184–2190. https://doi.org/10.1182/blood-2011-02-337840
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