Drug Resistance in Cancer Therapy and the Role of Epigenetics
Author:
Affiliation:
1. Department of Pediatrics, Nippon Medical School, Tokyo, Japan
Publisher
Medical Association of Nippon Medical School
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/jnms/87/5/87_JNMS.2020_87-508/_pdf
Reference46 articles.
1. 1. Holleman A, Cheok MH, den Boer ML, et al. Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment. N Engl J Med. 2004;351:533-42.
2. 2. Glasspool RM, Teodoridis JM, Brown R. Epigenetics as a mechanism driving polygenic clinical drug resistance. Br J Cancer. 2006;94:1087-92.
3. 3. Eden A, Gaudet F, Waghmare A, Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science. 2003;300:455.
4. 4. Asano T, Nakamura K, Fujii H, et al. Altered expression of topoisomerase IIα contributes to etoposide cross-resistant K562/MX2 cell line by aberrant methylation. Brit J Cancer. 2005;92:1486-92.
5. 5. Yamanishi M, Narazaki H, Asano T. Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase. Exp Hematol. 2015;43:207-14.
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