In vitro and in vivo effects of acetyldinaline on murine megakaryocytopoiesis

Author:

Volpe Donna A.,LoRusso Patricia M.,Foster Brenda J.,Parchment Ralph E.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference21 articles.

1. el-Beltagi HM, Martens AC, Lelieveld P, Haroun EA, Hagenbeek A (1993) Acetyldinaline: a new oral cytostatic drug with impressive differential activity against leukemic cells and normal stem cells?preclinical studies in a relevant rat model for human acute myelocytic leukemia. Cancer Res 53:3008

2. Foster BJ, Jones L, Wiegand R, LoRusso PM, Corbett TH (1997) Preclinical pharmacokinetic, antitumor and toxicity studies with CI-994 (N-acetyldinaline). Invest New Drugs 15:187

3. Gallichio VS, Scott KW, Hughes NK, Tse KF, Gaines H, Kirk PR, Birch NJ (1994) Increased hematopoietic toxicity following administration of interferon-? with combination dideoxynucleoside therapy (zidovudine plus ddI) administered in normal mice. Life Sci 56:PL71

4. Goris H, Bungart B, Loeffler M, Schmitz S, Nijhoh W (1990) Migration of stem cells and progenitors between marrow and spleen following thiamphenicol treatment of mice. Exp Hematol 18:400

5. Graziano MJ, Pilcher GD, Walsh KM, Kasali OB, Radulovic L (1997) Preclinical toxicity of a new oral anticancer drug, CI-994 (acetyldinaline), in rats and dogs. Invest New Drugs 15:295

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