Indomethacin overcomes doxorubicin resistance by decreasing intracellular content of glutathione and its conjugates with decreasing expression of γ-glutamylcysteine synthetase via promoter activity in doxorubicin-resistant leukemia cells

Author:

Asano Takeshi,Tsutsuda-Asano Arisa,Fukunaga Yoshitaka

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference24 articles.

1. Asano T, Zhi C-L, Hayakawa J, Fukunaga Y (2003) Analysis of resistance-related gene expression in doxorubicin resistant leukemia cell line by DNA microarray. Jpn J Pediatr Hematol 17:348–353

2. Brenner CA, Tam AW, Nelson PA, Engleman EG, Suzuki N, Fry KE, Larrick JW (1989) Message amplification phenotyping (MAPPing): a technique to simultaneously measure multiple mRNAs from small numbers of cells. Bio techniques 7:1096–1103

3. Cullen KV, Davey RA, Davey MW (2001) Verapamil-stimulated glutathione transport by the mutidrug resistance-associated protein (MRP1) in leukaemia cells. Biochem Pharmacol 62:417–424

4. van der Holt B, Lowenberg B, Burnett AK, Knauf WU, Shepherd J, Piccaluga PP, Ossenkoppele GJ, Verhoef GEG, Ferrant A, Crump M, Selleslag D, Theobald M, Fey MF, Vellenga E, Dugan M, Sonneveld P, on behalf of the Dutch-Belgian Hemato-Oncology Cooperative Group and the United Kingdom Medical Council. (2005) The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis. Blood 106:2646–2654

5. Iida T, Kijima H, Urata Y, Goto S, Ihara Y, Ola M, Kohno S, Scanlon KJ, Kondo T (2001) Hammerhead ribozyne against γ-glutamylcysteine synthetase sensitizes human colon cancer cells to cisplatin by downregulating both the glutathione synthesis and the expression of multiple drug resistance protein. Cancer Gene Ther 8:803–814

Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3