The cardioprotector monoHER does not interfere with the pharmacokinetics or the metabolism of the cardiotoxic agent doxorubicin in mice

Author:

Abou El Hassan Mohamed A. I.,Kedde Marc A.,Zwiers Ursula T. H.,Bast Aalt,van der Vijgh Wim J. F.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference21 articles.

1. Cini Neri G, Neri B, Bandinelli M, Del Tacca M, Danesi R, Riccardi R (1991) Anthracycline cardiotoxicity: in vivo and in vitro effects on biochemical parameters and heart ultrastructure of the rat. Oncology 48:327

2. Goeptar AR, Te Koppele JM, Lamme EK, Pique JM, Vermeulen NPE (1993) Cytochrome P-450 2B1-mediated one-electron reduction of adriamycin: a study with rat liver microsomes and purified enzymes. Mol Pharmacol 44:1267

3. Goeptar AR, Groot EJ, Scheerens H, Commandeur JNM, Vermeulen NPE (1994) Cytotoxicity of mitomycin C and adriamycin in freshly isolated rat hepatocytes: the role of cytochrome P450. Cancer Res 54:2411

4. Minotti G (1989) Adriamycin-dependent release of iron from microsomal membranes. Arch Biochem Biophys 268:398

5. Van der Vijgh WJF, Maessen PA, Pinedo HM (1990) Comparative metabolism and pharmacokinetics of doxorubicin and 4′-epidoxorubicin in plasma, heart and tumor of tumor-bearing mice. Cancer Chemother Pharmacol 26:9

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