In silico structural characterization of protein targets for drug development against Trypanosoma cruzi

Author:

Lima Carlyle Ribeiro,Carels Nicolas,Guimaraes Ana Carolina Ramos,Tufféry Pierre,Derreumaux Philippe

Funder

CAPES/CsF

Publisher

Springer Science and Business Media LLC

Subject

Computational Theory and Mathematics,Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Catalysis

Reference83 articles.

1. WHO (World Health Organization). http://www.who.int/topics/chagas_disease/en/

2. Noireau F, Diosque P, Jansen AM (2009) Trypanosoma cruzi: adaptation to its vectors and its hosts. Vet Res 40(2):1–23. doi: 10.1051/vetres/2009009

3. Viotti R, Vigliano C, Lococo B, Alvarez MG, Petti M, Bertocchi G, Armenti A (2009) Side effects of benznidazole as treatment in chronic Chagas disease: fears and realities. Expert Rev Anti-Infect 7(2):157–163. doi: 10.1586/14787210.7.2.157

4. Wilkinson SR, Taylor MC, Horn D, Kelly JM, Cheeseman I (2008) A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes. Proc Natl Acad Sci U S A 105(13):5022–5027

5. De Castro SL, Batista DGJ, Batista MM, Batista W, Dailyri A, Souza EM, Menna-Barreto RFS, Oliveira GM, Salomão K, Silva CF, Silva PB, Soeiro MNC (2011) Experimental chemotherapy for Chagas disease: a morphological, biochemical and proteomic overview of potential Trypanosoma cruzi targets of amidines derivatives and naphthoquinones. Mol Biol Int 306928

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