Hepatoprotective effects of phytochemicals berberine and umbelliferone against methotrexate-induced hepatic intoxication: experimental studies and in silico evidence
Author:
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Pollution,Environmental Chemistry,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s11356-021-15358-4.pdf
Reference71 articles.
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2. Akanda MR, Kim IS, Ahn D, Tae HJ, Tian W, Nam HH, Choo BK, Park BY (2017) In vivo and in vitro hepatoprotective effects of Geranium koreanum methanolic extract via downregulation of MAPK/caspase-3 pathway. Evid Based Complement Alternat Med 2017:8137627–8137612. https://doi.org/10.1155/2017/8137627
3. Ali N, Rashid S, Nafees S, Hasan SK, Shahid A, Majed F, Sultana S (2017) Protective effect of chlorogenic acid against methotrexate induced oxidative stress, inflammation and apoptosis in rat liver: an experimental approach. Chem Biol Interact 272:80–91. https://doi.org/10.1016/j.cbi.2017.05.002
4. Ali FEM, Hassanein EHM, Bakr AG, El-Shoura EAM, El-Gamal DA, Mahmoud AR, Abd-Elhamid TH (2020) Ursodeoxycholic acid abrogates gentamicin-induced hepatotoxicity in rats: role of NF-κB-p65/TNF-α, Bax/Bcl-xl/caspase-3, and eNOS/iNOS pathways. Life Sci 254:117760. https://doi.org/10.1016/j.lfs.2020.117760
5. Almani SA, Memon IA, Shaikh TZ, Khoharo HK, Ujjan I (2017) Berberine protects against metformin-associated lactic acidosis in induced diabetes mellitus. Iran J Basic Med Sci 20:511–515. https://doi.org/10.22038/ijbms.2017.8675
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