Pneumococcal whole-cell vaccine: optimization of cell growth of unencapsulated Streptococcus pneumoniae in bioreactor using animal-free medium

Author:

Liberman C.,Takagi M.,Cabrera-Crespo J.,Sbrogio-Almeida M. E.,Dias W. O.,Leite L. C. C.,Gonçalves V. M.

Publisher

Oxford University Press (OUP)

Subject

Applied Microbiology and Biotechnology,Biotechnology,Bioengineering

Reference10 articles.

1. Auzat I, Chapuy-Regaud S, Le Bras G, dos Santos D, Ogunniyi AD, Le Thomas I, Garel J-R, Paton JC, Trombe M-C (1999) The NADH oxidase of Streptococcus pneumoniae: its involvement in competence and virulence. Mol Microbiol 34:1018–1028

2. Baltz RH, Norris FH, Matsushima P, Dehoff BS, Rockey P, Porter G, Burgett S, Peery R, Hoskins J, Braverman L, Jenkins I, Solenberg P, Young M, McHenney MA, Rosteck PR Jr, Skatrud PL (2000) DNA sequence sampling and gene disruption for identification of new antibacterial targets in Streptococcus pneumoniae. In: Tomasz A (ed) Streptococcus pneumoniae: molecular biology and mechanisms of disease. Liebert, New York, pp 33–44

3. Berry AM, Lock RA, Hasman D, Paton JC (1989) Contribution of autolysin to virulence of Streptococcus pneumoniae. Infect Immun 57:2424–2430

4. Cartwright CP, Stock F, Gill VJ (1994) Improved enrichment broth for cultivation of fastidious organisms. J Clin Microbial 32:1825–1826

5. Chapuy-Regaud S, Duthoit F, Malfroy-Mastrorillo L, Gourdon P, Lindley ND, Trombe M-C (2001) Competence regulation by oxygen availability and Nox is not related to specific adjustment of central metabolism in Streptococcus pneumoniae. J Bacteriol 138:2957–2962

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