A Phase I, First-in-Human Study of PRL3-zumab in Advanced, Refractory Solid Tumors and Hematological Malignancies-Reference-Cited by-同舟云学术

A Phase I, First-in-Human Study of PRL3-zumab in Advanced, Refractory Solid Tumors and Hematological Malignancies

Published:2023-04-15 Issue:3 Volume:18 Page:391-402
ISSN:1776-2596
Container-title:Targeted Oncology
language:en
Short-container-title:Targ Oncol

Author:

Chee Cheng E.^ORCID,Ooi Melissa,Lee Soo-Chin,Sundar Raghav,Heong Valerie,Yong Wei-Peng,Ng Chin Hin,Wong Andrea,Lim Joline S. J.,Tan David S. P.,Soo Ross,Tan Joshua T. C.,Yang Song,Thura Min,Al-Aidaroos Abdul Qader,Chng Wee Joo,Zeng Qi,Goh Boon-Cher

Funder

National Medical Research Council

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Oncology

Link

https://link.springer.com/content/pdf/10.1007/s11523-023-00962-w.pdf

Reference18 articles.

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2. Zeng Q, Si X, Horstmann H, Xu Y, Hong W, Pallen CJ. Prenylation-dependent association of protein-tyrosine phosphatases PRL-1, -2, and -3 with the plasma membrane and the early endosome. J Biol Chem. 2000;275(28):21444–52.

3. Saha S, Bardelli A, Buckhaults P, Velculescu VE, Rago C, St Croix B, et al. A phosphatase associated with metastasis of colorectal cancer. Science. 2002;294:1343–6.

4. Al-Aidaroos AQ, Zeng Q. PRL-3 phosphatase and cancer metastasis. J Cell Biochem. 2010;111(5):1087–98.

5. Thura M, Al-Aidaroos AQO, Yong WP, Kono K, Gupta A, Lin YB, et al. PRL3-zumab, a first-in-class humanized antibody for cancer therapy. JCI Insight. 2016;1(9): e87607.

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