IMP Dehydrogenase and GTP as Targets in Human Leukemia Treatment

Author:

Weber George

Publisher

Springer US

Reference15 articles.

1. G. Weber, Biochemical strategy of cancer cells and the design of chemotherapy: G.H.A. Clowes Memorial Lecture, Cancer Res. 43: 3466 (1983).

2. R. C. Jackson, H. P. Morris and G. Weber, IMP dehydrogenase: A proliferation and malignancy-linked enzyme, Nature 256: 331 (1975).

3. G. Weber, N. Prajda and R. C. Jackson, Key enzymes of IMP metabolism: Transformation-and proliferation-linked alterations in gene expression, Advan. Enzyme Regul. 14:3 (1976).

4. G. Weber, M. Nagai, Y. Natsumeda, H. Nakamura, J. N. Eble, H. N. Jayaram, W. Zhen, E. Paulik, R. Hoffman and G. Tricot, Regulation of de novo and salvage pathways, Advan. Enzyme Regul. 31:45 (1991).

5. G. J. Tricot, H. N. Jayaram, E. Lapis, Y. Natsumeda, Y. Yamada, C. R. Nichols, P. Kneebone, N. Heerema, G. Weber and R. Hoffman, Biochemically directed therapy of leukemia with tiazofurin, a selective blocker of IMP dehydrogenase activity, Cancer Res. 49: 3696 (1989).

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