Antimetabolites Reduce the Activities of Enzymes with Short Half-Lives in Addition to Inhibiting their Specific Targets-Reference-Cited by-同舟云学术

Antimetabolites Reduce the Activities of Enzymes with Short Half-Lives in Addition to Inhibiting their Specific Targets

Published:1995 Issue: Volume: Page:145-150
ISSN:0065-2598
Container-title:Purine and Pyrimidine Metabolism in Man VIII
language:
Short-container-title:

Author:

Weber George,Prajda Noemi,Singhal Radhey L.

Publisher

Springer US

Link

http://link.springer.com/content/pdf/10.1007/978-1-4615-2584-4_33

Reference22 articles.

1. G. Weber, Biochemical strategy of cancer cells and the design of chemotherapy: G. H. A. Clowes Lecture, Cancer Res. 43: 3466 (1983).

2. T. Aoki, Initial steps of de novo pyrimidine nucleotide biosynthesis in parasites and mammalian tissues: purification, regulation, adaptation, and evolution, Jpn. J. Parasitology 43: 1 (1994).

3. G. Weber, S. Ichikawa, M. Nagai, and Y. Natsumeda, Azidothymidine inhibition of thymidine kinase and synergistic cytotoxicity with methotrexate and 5-fluorouracil in rat hepatoma and human colon cancer cells, Cancer Commun. 2: 129 (1990).

4. G. Weber, M. Nagai, N. Prajda, H. Nakamura, T. Szekeres, and E. Olah, AZT: a biochemical response modifier of methotrexate and 5-fluorouracil cytotoxicity in human ovarian and pancreatic carcinoma cells, Cancer Commun. 3: 127 (1991).

5. M. Abonyi, N. Prajda, Y. Hata, H. Nakamura, and G. Weber, Methotrexate decreases thymidine kinase activity, Biochem. Biophys. Res. Commun. 187: 522 (1992).

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1. Regulation of signal transduction;Advances in Enzyme Regulation;1995-01