Effects of Gαi2 and Gαz protein knockdown on alpha2A-adrenergic and cannabinoid CB1 receptor regulation of MEK-ERK and FADD pathways in mouse cerebral cortex
Author:
Funder
Ministerio de Ciencia, Innovación y Universidades
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s43440-021-00240-4.pdf
Reference70 articles.
1. Rajagopal S, Rajagopal K, Lefkowitz RJ. Teaching old receptors new tricks: biasing seven-transmembrane receptors. Nat Rev Drug Discov. 2010;9:373–86. https://doi.org/10.1038/nrd3024.
2. Shenoy SK, Lefkowitz RJ. β-Arrestin-mediated receptor trafficking and signal transduction. Trends Pharmacol Sci. 2011;32:521–33. https://doi.org/10.1016/j.tips.2011.05.002.
3. Mullard A. FDA approves first GPCR biased agonist. Nat Rev Drug Discov. 2020;19:659. https://doi.org/10.1038/d41573-020-00159-0.
4. Manglik A, Lin H, Aryal DK, McCorvy JD, Dengler D, Corder G, et al. Structure-based discovery of opioid analgesics with reduced side effects. Nature. 2016;537:185–90. https://doi.org/10.1038/nature19112.
5. Kudla L, Bugno R, Skupio U, Wiktorowska L, Solecki W, Wojtas A, et al.. Functional characterization of a novel opioid, PZM21, and its effects on the behavioural responses to morphine. Br J Pharmacol. 2019;176:4434–45. https://doi.org/10.1111/bph.14805.
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1. Cannabinoid CB2 receptor ligands disrupt the sequential regulation of p-MEK1/2 to p-ERK1/2 in mouse brain cortex;Exploration of Neuroprotective Therapy;2023-10-24
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