Functional characterization of a novel opioid, PZM21, and its effects on the behavioural responses to morphine-Reference-Cited by-同舟云学术

Functional characterization of a novel opioid, PZM21, and its effects on the behavioural responses to morphine

Published:2019-12 Issue:23 Volume:176 Page:4434-4445
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Kudla Lucja¹^ORCID,Bugno Ryszard²,Skupio Urszula¹^ORCID,Wiktorowska Lucja¹,Solecki Wojciech¹,Wojtas Adam³,Golembiowska Krystyna³,Zádor Ferenc⁴,Benyhe Sándor⁴,Buda Szymon⁵^ORCID,Makuch Wioletta⁶,Przewlocka Barbara⁶,Bojarski Andrzej J.²,Przewlocki Ryszard¹^ORCID

Affiliation:

1. Department of Molecular Neuropharmacology, Maj Institute of PharmacologyPolish Academy of Sciences Krakow Poland

2. Department of Medicinal Chemistry, Maj Institute of PharmacologyPolish Academy of Sciences Krakow Poland

3. Department of Pharmacology, Maj Institute of PharmacologyPolish Academy of Sciences Krakow Poland

4. Institute of Biochemistry, Biological Research CentreHungarian Academy of Sciences Szeged Hungary

5. Department of Organic Chemistry, Faculty of ChemistryJagiellonian University Krakow Poland

6. Department of Pain Pharmacology, Maj Institute of PharmacologyPolish Academy of Sciences Krakow Poland

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.14805

Reference56 articles.

1. Nalbuphine could decrease the rewarding effect induced by tramadol in mice while enhancing its antinociceptive activity

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4. Effects of acute and repeated treatment with the biased mu opioid receptor agonist TRV130 (oliceridine) on measures of antinociception, gastrointestinal function, and abuse liability in rodents

5. The G-protein biased mu-opioid agonist, TRV130, produces reinforcing and antinociceptive effects that are comparable to oxycodone in rats

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