Idarubicin metabolism and pharmacokinetics after intravenous and oral administration in cancer patients: a crossover study

Author:

Camaggi Carlo M.,Strocchi Elena,Carisi Patrizia,Martoni Andrea,Tononi Alessandra,Guaraldi Monica,Strolin-Benedetti Margherita,Efthymiopoulos Constantin,Pannuti Franco

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference28 articles.

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2. Berman E, Wittes RE, Leyland-Jones B, Casper ES, Gralla RJ, Howard J, Williams L, Baratz R, Young CW (1983) Phase I and clinical pharmacology studies of intravenous and oral administration of 4-demethoxy daunorubicin in patients with advanced cancer. Cancer Res 43: 6096?6101

3. Camaggi CM, Strocchi E, Tamassia V, Martoni A, Giovannini M, Iafelice G, Canova N, Marraro D, Martini A, Pannuti F (1982) Pharmacokinetic studies of 4?-epidoxorubicin in cancer patients with normal and impaired renal functions and with hepatic metastases. Cancer Treat Rep 66: 1819?1824

4. Camaggi CM, Strocchi E, Martoni A, Angelelli B, Comparsi R, Pannuti F (1985) Epirubicin plasma and blood pharmacokinetics after single IV bolus in advanced cancer patients. Drugs Expt Clin Res 11: 285?294

5. Camaggi CM, Comparsi R, Strocchi E, Testoni F, Angelelli B, Pannuti F (1988) Epirubicin and doxorubicin comparative metabolism and pharmacokinetics. Cancer Chemother Pharmacol 21: 221?228

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