An Algorithm and R Program for Fitting and Simulation of Pharmacokinetic and Pharmacodynamic Data

Author:

Li Jijie,Yan Kewei,Hou Lisha,Du Xudong,Zhu Ping,Zheng Li,Zhu Cairong

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference38 articles.

1. Bretz F, Dette H, Pinheiro JC. Practical considerations for optimal designs in clinical dose finding studies. Stat Med. 2010;29(7–8):731–42.

2. Schmidt R. Dose-finding study in clinical drug development. Eur J Clin Pharmacol. 1988;34(1):15–9.

3. Rockville. General Considerations for the Clinical Evaluation of Drugs. In: U.S. Department of Health E, and Welfare, Public Health Service, Food and Drug Administration, editor. United States. Food and Drug Administration. Bureau of Drugs; 1977.

4. Greenwood DT, Todd AH. From laboratory to clinical use. In: Johnson FN, Johnson S, editors. Clinical Trials. London, Edinburgh: Blackwell Oxford; 1977. p. 13–35.

5. Nielsen EI, Friberg LE. Pharmacokinetic-pharmacodynamic modeling of antibacterial drugs. Pharmacol Rev. 2013;65(3):1053–90. doi: 10.1124/pr.111.005769 .

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