Predicting transdermal fentanyl delivery using physics-based simulations for tailored therapy based on the age
Author:
Affiliation:
1. Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Biomimetic Membranes and Textiles, St. Gallen, Switzerland
2. ARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland
Funder
Novartis Research Foundation
Publisher
Informa UK Limited
Subject
Pharmaceutical Science,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/10717544.2022.2050846
Reference68 articles.
1. Opioid-induced respiratory depression in humans: a review of pharmacokinetic–pharmacodynamic modelling of reversal
2. Pharmacokinetic/Pharmacodynamic Relationships of Transdermal Buprenorphine and Fentanyl in Experimental Human Pain Models
3. Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes
4. Pharmacokinetic Characterisation of Transdermal Delivery Systems
5. Application of Physiologic Models to Predict the Influence of Changes in Body Composition and Blood Flows on the Pharmacokinetics of Fentanyl and Alfentanil in Patients
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