Novel Compounds Identified by Structure-Based Prion Disease Drug Discovery Using In Silico Screening Delay the Progression of an Illness in Prion-Infected Mice-Reference-Cited by-同舟云学术

Novel Compounds Identified by Structure-Based Prion Disease Drug Discovery Using In Silico Screening Delay the Progression of an Illness in Prion-Infected Mice

Published:2020-08-06 Issue:4 Volume:17 Page:1836-1849
ISSN:1933-7213
Container-title:Neurotherapeutics
language:en
Short-container-title:Neurotherapeutics

Author:

Ishibashi Daisuke,Ishikawa Takeshi,Mizuta Satoshi,Tange Hiroya,Nakagaki Takehiro,Hamada Tsuyoshi,Nishida Noriyuki

Funder

Ministry of Health, Labour and Welfare

Japan Agency for Medical Research and Development

Takeda Science Foundation

Japan Intractable Disease Research Foundation

Tokyo Biochemical Research Foundation

YOKOYAMA Foundation for Clinical Pharmacology

Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care

Mochida Memorial Foundation for Medical and Pharmaceutical Research

Waksman Foundation of Japan

the Center for Clinical and Translational Research of Kyushu University Hospital

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Neurology (clinical),Pharmacology

Link

https://link.springer.com/content/pdf/10.1007/s13311-020-00903-9.pdf

Reference51 articles.

1. Shyng SL, Lehmann S, Moulder KL, Harris DA. Sulfated glycans stimulate endocytosis of the cellular isoform of the prion protein, PrPC, in cultured cells. J Biol Chem. 1995;270(50):30221-9.

2. Mange A, Nishida N, Milhavet O, McMahon HE, Casanova D, Lehmann S. Amphotericin B inhibits the generation of the scrapie isoform of the prion protein in infected cultures. Journal of Virology. 2000;74(7):3135-40.

3. Marella M, Lehmann S, Grassi J, Chabry J. Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release. The Journal of Biological Chemistry. 2002;277(28):25457-64.

4. Kiachopoulos S, Heske J, Tatzelt J, Winklhofer KF. Misfolding of the prion protein at the plasma membrane induces endocytosis, intracellular retention and degradation. Traffic. 2004;5(6):426-36.

5. Homma T, Ishibashi D, Nakagaki T, Fuse T, Mori T, Satoh K, et al. Ubiquitin-specific protease 14 modulates degradation of cellular prion protein. Scientific Reports. 2015;5:11028.

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases?;Biochemical Journal;2023-08-16