Lag times to steady state drug delivery by continuous intravenous infusion: direct comparison of peristaltic and syringe pump performance identifies contributions from infusion system dead volume and pump startup characteristics

Author:

Gibson Lauren E.ORCID,Knudsen Anders S.,Arney David,Deng Hao,Sims Nathaniel M.,Peterfreund Robert A.

Funder

development grant from the dept of anesthesia, critical care, and pain medicine at massachusetts general hospital

Publisher

Springer Science and Business Media LLC

Subject

Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine,Health Informatics

Reference17 articles.

1. Bartels K, Moss DR, Peterfreund RA. An analysis of drug delivery dynamics via a pediatric central venous infusion system: quantification of delays in achieving intended doses. Anesth Analg. 2009;109:1156–61.

2. Moss DR, Bartels K, Peterfreund GL, Lovich MA, Sims NM, Peterfreund RA. An in vitro analysis of central venous drug delivery by continuous infusion: the effect of manifold design and port selection. Anesth Analg. 2009;109:1524–9.

3. Lovich MA, Doles J, Peterfreund RA. The impact of carrier flow rate and infusion set dead-volume on the dynamics of intravenous drug delivery. Anesth Analg. 2005;100:1048–55.

4. Lovich MA, Peterfreund GL, Sims NM, Peterfreund RA. Central venous catheter infusions: a laboratory model shows large differences in drug delivery dynamics related to catheter dead volume. Crit Care Med. 2007;35:2792–8.

5. Lovich MA, Peterfreund RA. Drug flow through clinical infusion systems: how modeling of the common-volume helps explain clinical events. Pharm Technol Hosp Pharm. 2017;2:49–61.

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