Detailed chromosome analysis of wild-type, immortalized fibroblasts with SV40T, E6E7, combinational introduction of cyclin dependent kinase 4, cyclin D1, telomerase reverse transcriptase
Author:
Funder
Graduate School of Engineering, Iwate University
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Developmental Biology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s11626-021-00631-0.pdf
Reference18 articles.
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2. Donai K, Kiyono T, Eitsuka T et al (2014) Bovine and porcine fibroblasts can be immortalized with intact karyotype by the expression of mutant cyclin dependent kinase 4, cyclin D, and telomerase. J Biotechnol 176:50–57. https://doi.org/10.1016/j.jbiotec.2014.02.017
3. Dyson NJ (2016) RB1: a prototype tumor suppressor and an enigma. Genes Dev 30:1492–1502
4. Fukuda T, Eitsuka T, Donai K et al (2018) Expression of human mutant cyclin dependent kinase 4, cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta). Sci Rep. https://doi.org/10.1038/s41598-018-27271-x
5. Fukuda T, Furuya K, Takahashi K et al (2021) Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells. iScience. https://doi.org/10.1016/j.isci.2020.101929
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