Inhibition of apoptosis, activation of NKT cell and upregulation of CD40 and CD40L mediated by M. leprae antigen(s) combined with Murabutide and Trat peptide in leprosy patients

Author:

Chattree Vineeta,Khanna Neena,Bisht Vandana,Rao D. N.

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,General Medicine

Reference41 articles.

1. Choudhuri K (1995) The immunology of leprosy; unraveling an enigma. Int J Lepr Other Mycobact Dis 63:430–447

2. Yamamura M, Uyemura K, Deans RJ et al (1991) Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science 254:277–279

3. Sieling PA, Abrams JS, Yamamura M et al (1993) Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in leprosy. J Immunol 150:5501–5510

4. Groux H , Bigler M, de Vries JE et al (1996) Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells. J Exp Med 184:1–8

5. Flores Villanueva PO, Reiser H, Stadecker MJ (1994) Regulation of T helper cell responses in experimental murine schistosomiasis by IL-10. Effect on expression of B7-1 and B7-2 costimulatory molecules by macrophages. J Immunol 153:5190–5199

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