Library Synthesis: Building Block Selection, Handling, and Tracking
Author:
Publisher
Springer US
Link
https://link.springer.com/content/pdf/10.1007/978-1-0716-2545-3_1
Reference30 articles.
1. Clark MA, Acharya RA, Arico-Muendel CC, Belyanskaya SL, Benjamin DR, Carlson NR et al (2009) Design, synthesis and selection of DNA-encoded small-molecule libraries. Nat Chem Biol 5(9):647–654. https://doi.org/10.1038/nchembio.211
2. Deng H, Zhou J, Sundersingh FS, Summerfield J, Somers D, Messer JA et al (2015) Discovery, SAR, and X-ray binding mode study of BCATm inhibitors from a novel DNA-encoded library. ACS Med Chem Lett 6(8):919–924. https://doi.org/10.1021/acsmedchemlett.5b00179
3. Litovchick A, Dumelin CE, Habeshian S, Gikunju D, Guié MA, Centrella P et al (2015) Encoded library synthesis using chemical ligation and the discovery of sEH inhibitors from a 334-million member library. Sci Rep 5:10916. https://doi.org/10.1038/srep10916
4. Kollmann CS, Bai X, Tsai CH, Yang H, Lind KE, Skinner SR et al (2014) Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists. Bioorg Med Chem 22(7):2353–2365. https://doi.org/10.1016/j.bmc.2014.01.050
5. Harris PA, King BW, Bandyopadhyay D, Berger SB, Campobasso N, Capriotti CA et al (2016) DNA-encoded library screening Identifies Benzo[b][1,4]oxazepin-4-ones as highly potent and monoselective receptor interacting Protein 1 Kinase inhibitors. J Med Chem 59(5):2163–2178. https://doi.org/10.1021/acs.jmedchem.5b01898
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