Cell-Based hERG Channel Inhibition Assay in High-Throughput Format
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Publisher
Springer US
Link
https://link.springer.com/content/pdf/10.1007/978-1-0716-2213-1_3
Reference9 articles.
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2. Tseng GN (2001) I(Kr): the hERG channel. J Mol Cell Cardiol 33(5):835–849. https://doi.org/10.1006/jmcc.2000.1317
3. Kamiya K, Niwa R, Morishima M, Honjo H, Sanguinetti MC (2008) Molecular determinants of hERG channel block by terfenadine and cisapride. J Pharmacol Sci 108(3):301–307. https://doi.org/10.1254/jphs.08102fp
4. Zhang KP, Yang BF, Li BX (2014) Translational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspects. Acta Pharmacol Sin 35(12):1473–1484. https://doi.org/10.1038/aps.2014.101
5. Chiu PJ, Marcoe KF, Bounds SE, Lin CH, Feng JJ, Lin A, Cheng FC, Crumb WJ, Mitchell R (2004) Validation of a [3H]astemizole binding assay in HEK293 cells expressing HERG K+ channels. J Pharmacol Sci 95(3):311–319. https://doi.org/10.1254/jphs.fpe0040101
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