Wnt/β-catenin signaling inhibits the Shh pathway and impairs tumor growth in Shh-dependent medulloblastoma-Reference-Cited by-同舟云学术

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Wnt/β-catenin signaling inhibits the Shh pathway and impairs tumor growth in Shh-dependent medulloblastoma

Published:2014-02-15 Issue:4 Volume:127 Page:605-607
ISSN:0001-6322
Container-title:Acta Neuropathologica
language:en
Short-container-title:Acta Neuropathol

Author:

Pöschl Julia,Bartels Martin,Ohli Jasmin,Bianchi Edoardo,Kuteykin-Teplyakov Konstantin,Grammel Daniel,Ahlfeld Julia,Schüller Ulrich

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology (clinical),Pathology and Forensic Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00401-014-1258-2.pdf

Reference13 articles.

1. Anne SL, Govek EE, Ayrault O et al (2013) WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation. PLoS ONE 8:e81769. doi: 10.1371/journal.pone.0081769

2. Goodrich LV, Milenkovic L, Higgins KM, Scott MP (1997) Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277:1109–1113

3. Grammel D, Warmuth-Metz M, von Bueren AO et al (2012) Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem. Acta Neuropathol 123:601–614. doi: 10.1007/s00401-012-0961-0

4. Harada N, Tamai Y, Ishikawa T et al (1999) Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J 18:5931–5942. doi: 10.1093/emboj/18.21.5931

5. Jaworski T, Dewachter I, Lechat B et al (2011) GSK-3alpha/beta kinases and amyloid production in vivo. Nature 480:E4–E5. doi: 10.1038/nature10615 (discussion E6)

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