MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status-Reference-Cited by-同舟云学术

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

Published:2012-07-19 Issue:4 Volume:124 Page:547-560
ISSN:0001-6322
Container-title:Acta Neuropathologica
language:en
Short-container-title:Acta Neuropathol

Author:

Bady Pierre,Sciuscio Davide,Diserens Annie-Claire,Bloch Jocelyne,van den Bent Martin J.,Marosi Christine,Dietrich Pierre-Yves,Weller Michael,Mariani Luigi,Heppner Frank L.,Mcdonald David R.,Lacombe Denis,Stupp Roger,Delorenzi Mauro,Hegi Monika E.

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Neurology (clinical),Pathology and Forensic Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00401-012-1016-2

Reference53 articles.

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4. Du P, Zhang X, Huang CC et al (2010) Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis. BMC Bioinformatics 11:587

5. Esteller M, Garcia-Foncillas J, Andion E et al (2000) Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343:1350–1354

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