Identification of 1-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory agent, and its metabolites in rat liver subcellular fractions-Reference-Cited by-同舟云学术

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Identification of 1-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory agent, and its metabolites in rat liver subcellular fractions

Published:2006-11 Issue:11 Volume:29 Page:984-989
ISSN:0253-6269
Container-title:Archives of Pharmacal Research
language:en
Short-container-title:Arch Pharm Res

Author:

Lee Sang Kyu,Jeon Tae Won,Basnet Arjun,Jeong Hye Gwang,Lee Eung Seok,Jeong Tae Cheon

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Drug Discovery,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/BF02969282.pdf

Reference11 articles.

1. Clement, B., Demesmaeker, M., and Linne, S., Microsomal catalyzedN-hydroxylation of guanabenz and reduction of theN-hydroxylated metabolites: characterization of the two reactions and genotoxic potential of guanoxabenz.Chem. Res. Toxicol., 9, 682–688 (1996).

2. Jahng, Y., Zhao, L. X., Moon, Y. S., Basnet, A., Kim, E. K., Chang, H. W., Ju, H. K., Jeong, T. C., and Lee, E. S., Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities.Bioorg. Med. Chem. Lett., 24, 2559–2562 (2004).

3. Lee, E. S., Ju, H. K., Moon, T. C., Lee, E., Jahng, Y., Lee, S. H., Son, J. K., Baek, S. H., and Chang, H. W., Inhibition of nitric oxide and tumor necrosis factor-α production by propenone compound through blockade of nuclear factor-kB activation in cultured murine macrophages.Biol. Pharm. Bull., 27, 617–620 (2004).

4. Lee, E. S., Park, B. C., Paek, S. H., Lee, Y. S., Basnet, A., Jin, D. Q., Choi, H. G., Yong, C. S., and Kim, J. A., Potent analgesic and anti-inflammatory activities of 1-furan-2-yl-3-pyridin-2-yl-propenone with gastric ulcer sparing effect.Biol. Pharm. Bull., 29, 361–364 (2006).

5. Lowry, O. H., Rosenbrough, N. J., Farr, A. L., and Randall, R. J., Protein measurement with the folin phenol reagent.J. Biol. Chem., 193, 265–275 (1951).

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. In vitro characterization of the enzymes involved in the metabolism of 1-Furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory propenone compound;Archives of Pharmacal Research;2008-06

2. The effect of 1-furan-2-yl-3-pyridine-2-yl-propenone on pharmacokinetic parameters of warfarin;Archives of Pharmacal Research;2007-07

3. Metabolism of FPP-3, an Anti-inflammatory Propenone Compound, in Rat by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry;Biological and Pharmaceutical Bulletin;2007

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