Blood Oxygen Level–Dependent (BOLD) MRI in Renovascular Hypertension
Author:
Publisher
Springer Science and Business Media LLC
Subject
Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11906-011-0218-7.pdf
Reference41 articles.
1. • de Mast Q, Beutler JJ. The prevalence of atherosclerotic renal artery stenosis in risk groups: a systematic literature review. J Hypertens 2009; 27:1333–1340. This useful assembly of previous publications identifies ARAS as part of imaging for other indications. Of patients with suspected “renovascular hypertension,” 14.1% were positive for ARAS. Use of a low threshold (50% occlusion) and single publications regarding end-stage renal disease and congestive heart failure have overstated the risk.
2. Hackam DG, Duong-Hua ML, Mamdani M, Li P, Tobe SW, Spence JD, et al. Angiotensin inhibition in renovascular disease: a population-based cohort study. Am Heart J. 2008;156:549–55.
3. •• The ASTRAL Investigators. Revascularization versus medical therapy for renal-artery stenosis. N Engl J Med 2009; 361:1953–1962. This important but limited study selected 806 subjects by “uncertainty” as to whether they would benefit from revascularization as compared with medical therapy alone. Remarkably stable levels of kidney function overall did not differ between groups. These data emphasize the success and stability of medical therapy alone for many patients with ARAS for several years. More than 40% of the patients were in the category of 50% to 70% stenosis, which likely diluted the power of this trial.
4. Bax L, Woittiez AJ, Kouwenberg HJ, Mali PTM, Buskens E, Beek FJA, et al. Stent placement in patients with atherosclerotic renal artery stenosis and impaired renal function. Ann Intern Med. 2009;150:840–8.
5. Textor SC, McKusick MA, Misra S, Glockner J. Timing and selection for renal revascularization in an era of negative trials: what to do? Prog Cardiovasc Dis. 2009;52:220–8.
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