Novel LC–MS/MS method for estimation of niacin with negligible matrix effect and its application to the BE study

Author:

Vats Poonam,Verma S. Manaswita,Monif Tausif

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Pharmaceutical Science

Reference16 articles.

1. Guidance for industry: bioanalytical method validation (2013) US Food and Drug. http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM368107.pdf . Accessed 09 Nov 2014

2. Guideline on bioanalytical method validation (2011) European Medicines Agency: Guideline on bioanalytical method validation http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2011/08/WC500109686.pdf . Accessed 09 Nov 2014

3. Hseih Y, Chen J (2005) Simulations determination of nicotinic acid and its metabolite using hydrophilic interaction chromatography with tandem mass spectrometry. Rapid Commun Mass Spectrom 19(21):3031–3036

4. Product Monograph, PrNIASPAN® (2015) http://www.sunovion.ca/monographs/niaspan.pdf . Accessed 28 March 2016

5. Inamadugu JK, Damaramadugu R, Mullangi R, Ponneri V (2010) Simultaneous determination of niacin and its metabolites-nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide in human plasma by LC-MS/MS and its application to a human pharmacokinetic study. Biomed Chromatogr 24(10):1059–1074

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