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The LRRK2 signalling system

  • Published:2018-01-08 Issue:1 Volume:373 Page:39-50
  • ISSN:0302-766X
  • Container-title:Cell and Tissue Research
  • language:en
  • Short-container-title:Cell Tissue Res

Author:

Price Alice,Manzoni Claudia,Cookson Mark R.,Lewis Patrick A.

Funder

Medical Research Council

Parkinson's UK

National Institute on Aging

Biotechnology and Biological Sciences Research Council

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Histology,Pathology and Forensic Medicine

Reference84 articles.

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2. Alegre-Abarrategui J, Christian H, Lufino MMP, Mutihac R, Venda LL, Ansorge O, Wade-Martins R (2009) LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model. Hum Mol Genet 18(21):4022–4034. https://doi.org/10.1093/hmg/ddp346 Oxford University Press

3. Atashrazm F, Dzamko N (2016) LRRK2 inhibitors and their potential in the treatment of Parkinson’s disease. Curr Perspect Clin Pharmacol Adv Applic 8:177–189. doi: https://doi.org/10.2147/CPAA.S102191

4. Aylett CHS, Sauer E, Imseng S, Boehringer D, Hall MN, Ban N, Maier T (2016) Architecture of human mTOR complex 1. Science 351(6268):48–52. https://doi.org/10.1126/science.aaa3870

5. Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, NIDDK IBD Genetics Consortium, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot J-P, de Vos M, Vermeire S, Louis E, Belgian-French IBD Consortium, Wellcome Trust Case Control Consortium, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwilliam R, Tremelling M, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ (2008) Genome-wide association defines more than 30 distinct susceptibility loci for Crohn’s disease. Nat Genet 40(8):955–962. https://doi.org/10.1038/ng.175 NIH Public Access

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