Dosing in Children: A Critical Review of the Pharmacokinetic Allometric Scaling and Modelling Approaches in Paediatric Drug Development and Clinical Settings

Author:

Mahmood Iftekhar

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology

Reference131 articles.

1. Kearns GL, Abdel-Rahman SM, Alander SW, et al. Developmental pharmacology: drug disposition, action, and therapy in infants and children. N Engl J Med. 2003;349:1157–67.

2. Mahmood I. Prediction of drug clearance in children: impact of allometric exponents, body weight and age. Ther Drug Monit. 2007;29:271–8.

3. Weiss CF, Glazko A, Weston JK. Chloramphenicol in the new born infant. N Engl J Med. 1960;262:787–94.

4. Silverman WA, Anderson DH, Blanc WA, et al. A difference in mortality rate and incidence of kernicterus among premature infants allotted to two prophylactic anti-bacterial regimens. Pediatrics. 1956;18:614–25.

5. Gibaldi M. Gastrointestinal absorption: physicochemical considerations. In: Biopharmaceutics and clinical pharmacokinetics. 3rd ed. Philadelphia: Lea and Febiger; 1984. p. 44–63.

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