Prediction of Maternal and Fetal Doravirine Exposure by Integrating Physiologically Based Pharmacokinetic Modeling and Human Placenta Perfusion Experiments
Author:
Funder
Merck Sharp and Dohme
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology
Link
https://link.springer.com/content/pdf/10.1007/s40262-022-01127-0.pdf
Reference50 articles.
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3. Hodel EM, Marzolini C, Waitt C, Rakhmanina N. Pharmacokinetics, placental and breast milk transfer of antiretroviral drugs in pregnant and lactating women living with HIV. Curr Pharm Des. 2019;25(5):556–76. https://doi.org/10.2174/1381612825666190320162507.
4. EACS. the European Guidelines for the treatment of HIV-positive adults in Europe: version 11.0. 2021. https://www.eacsociety.org/media/final2021eacsguidelinesv11.0_oct2021.pdf. Accessed 1 Nov 2021.
5. Yee KL, Cabalu TD, Kuo Y, Fillgrove KL, Liu Y, Triantafyllou I, et al. Physiologically based pharmacokinetic modeling of doravirine and its major metabolite to support dose adjustment with rifabutin. J Clin Pharmacol. 2021;61(3):394–405. https://doi.org/10.1002/jcph.1747.
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