Total Clearance and Organ Clearance

Author:

Talevi Alan,Bellera Carolina L.

Publisher

Springer International Publishing

Reference26 articles.

1. Toutain PL, Bousquet-Mélou A. Plasma clearance. J Vet Pharmacol Ther. 2004;27(6):415–25.

2. Horde GW, Gupta V. Drug clearance. [Updated 2020 Oct 11]. In: StatPearls [Internet]. Treasure Island: StatPearls Publishing; 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557758/.

3. Pang KS, Rowland M. Hepatic clearance of drugs. I. Theoretical considerations of a “well-stirred” model and a “parallel tube” model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance. J Pharmacokinet Biopharm. 1977;5:625–53.

4. Smith DA, Beaumont K, Maurer TS, Di L. Clearance in drug design. J Med Chem. 2019;62:2245–55.

5. Uchimura T, Kato M, Saito T, Kinoshita H. Prediction of human blood-to-plasma drug concentration ratio. Biopharm Drug Dispos. 2010;31:286–97.

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