Myelodysplastic Neoplasms/Syndromes (MDS)

Author:

Robin Marie,Gurnari Carmelo

Abstract

AbstractMyelodysplastic neoplasms/syndromes (MDS) are a heterogeneous group of clonal stem cell disorders characterized by peripheral cytopenias and dysplastic features in blood and bone marrow.

Publisher

Springer International Publishing

Reference34 articles.

1. Arber DA, Orazi A, Hasserjian RP, Borowitz MJ, Calvo KR, Kvasnicka H-M, Wang SA, et al. International consensus classification of myeloid neoplasms and acute Leukemias: integrating morphologic, clinical, and genomic data. Blood. 2022;140(11):1200–28. https://doi.org/10.1182/blood.2022015850.

2. Bejanyan N, Zhang M, Bo-Subait K, Brunstein C, Wang H, Warlick ED, Giralt S, et al. Myeloablative conditioning for allogeneic transplantation results in superior disease-free survival for acute myelogenous leukemia and myelodysplastic syndromes with low/intermediate but not high disease risk index: a center for international blood and marrow transplant research study. Transplant Cell Ther. 2021;27(1):68.e1–9. https://doi.org/10.1016/j.bbmt.2020.09.026.

3. Craddock C, Labopin M, Robin M, Finke J, Chevallier P, Yakoub-Agha I, Bourhis JH, et al. Clinical activity of Azacitidine in patients who relapse after allogeneic stem cell transplantation for acute myeloid leukemia. Haematologica. 2016;101(7):879–83. https://doi.org/10.3324/haematol.2015.140996.

4. Craddock C, Jackson A, Loke J, Siddique S, Hodgkinson A, Mason J, Andrew G, et al. Augmented reduced-intensity regimen does not improve postallogeneic transplant outcomes in acute Myeloid Leukemia. J Clin Oncol. 2021;39(7):768–78. https://doi.org/10.1200/JCO.20.02308.

5. Cutler CS, Lee SJ, Greenberg P, Deeg HJ, Perez WS, Anasetti C, Bolwell BJ, et al. A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: delayed transplantation for low-risk myelodysplasia is associated with improved outcome. Blood. 2004;104(2):579–85.

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