Saffron (Crocins) Against Cancer

Author:

Bhia Mohammed,Rajani Huda Fatima,Mohammadkhani Niloufar,Jafari Seid Mahdi

Publisher

Springer International Publishing

Reference176 articles.

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2. Ahmadabadi F, Saghebjoo M, Huang C-J, Saffari I, Zardast M (2020) The effects of high-intensity interval training and saffron aqueous extract supplementation on alterations of body weight and apoptotic indices in skeletal muscle of 4T1 breast cancer-bearing mice with cachexia. Appl Physiol Nutr Metab 45(5):555–563. https://doi.org/10.1139/apnm-2019-0352

3. Akhondzadeh S, Sabet MS, Harirchian MH, Togha M, Cheraghmakani H, Razeghi S, Hejazi SS, Yousefi MH, Alimardani R, Jamshidi A, Zare F, Moradi A (2010) Saffron in the treatment of patients with mild to moderate Alzheimer’s disease: a 16-week, randomized and placebo-controlled trial. J Clin Pharm Ther 35(5):581–588. https://doi.org/10.1111/j.1365-2710.2009.01133.x

4. Al-Hrout A, Chaiboonchoe A, Khraiwesh B, Murali C, Baig B, El-Awady R, Tarazi H, Alzahmi A, Nelson DR, Greish YE, Ramadan W, Salehi-Ashtiani K, Amin A (2018) Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells. Sci Rep 8(1):1–15. https://doi.org/10.1038/s41598-018-34855-0

5. Amerizadeh F, Rezaei N, Rahmani F, Hassanian SM, Moradi-Marjaneh R, Fiuji H, Boroumand N, Nosrati-Tirkani A, Ghayour-Mobarhan M, Ferns GA, Khazaei M, Avan A (2018) Crocin synergistically enhances the antiproliferative activity of 5-flurouracil through Wnt/PI3K pathway in a mouse model of colitis-associated colorectal cancer. J Cell Biochem 119(12):10250–10261. https://doi.org/10.1002/jcb.27367

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