Spontaneous remission of 2-chlorodeoxyadenosine (2-CdA)-related secondary myelodysplastic syndrome in a patient with refractory Langerhans cell histiocytosis

Author:

Suzuki Daisuke,Kobayashi Ryoji,Sano Hirozumi,Kishimoto Kenji,Yasuda Kazue,Nakanishi Masanori,Nagashima Tetsuro,Kobayashi Kunihiko

Publisher

Springer Science and Business Media LLC

Subject

Hematology

Reference20 articles.

1. Stine KC, Saylors RL, Williams LL, Becton DL. 2-Chlorodeoxyadenosine (2-CdA) for the treatment of refractory or recurrent Langerhans cell histiocytosis (LCH) in pediatric patients. Med Pediatr Oncol. 1997;29:288–92.

2. Apollonsky N, Lipton JM. Treatment of refractory Langerhans cell histiocytosis (LCH) with a combination of 2-chlorodeoxyadenosine and cytosine arabinoside. J Pediatr Hematol Oncol. 2009;31:53–6.

3. Weitzman S, Wayne AS, Arceci R, Lipton JM, Whitlock JA. Nucleoside analogues in the therapy of Langerhans cell histiocytosis: a survey of members of the histiocyte society and review of the literature. Med Pediatr Oncol. 1999;33:476–81.

4. Jager G, Hofler G, Linkesch W, Neumeister P. Occurrence of a myelodysplastic syndrome (MDS) during first-line 2-chlorodeoxyadenosine (2-CdA) treatement of a low-grade gastrointestinal MALT lymphoma. Case report and review of the literature. Haematologica. 2004;89:e1–3.

5. Van Den Neste E, Louviaux I, Michaux JL, Delannoy A, Hagemeijer A, Scheiff JM, Bosly A, Straetmans N, Ferrant A. Myelodysplastic syndrome with monosomy 5 and/or 7 following therapy with 2-chloro-2′-deoxyadenosine. Br J Haematol. 1999;105:268–70.

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