In vitro evaluation of 9-(2-phosphonylmethoxyethyl)adenine ester analogues, a series of anti-HBV structures with improved plasma stability and liver release-Reference-Cited by-同舟云学术

In vitro evaluation of 9-(2-phosphonylmethoxyethyl)adenine ester analogues, a series of anti-HBV structures with improved plasma stability and liver release

Published:2013-12-12 Issue:11 Volume:37 Page:1416-1425
ISSN:0253-6269
Container-title:Archives of Pharmacal Research
language:en
Short-container-title:Arch. Pharm. Res.

Author:

Liao Sha,Fan Shi-Yong,Liu Qin,Li Chang-Kun,Chen Jia,Li Jing-Lai,Zhang Zhi-Wei,Zhang Zhen-Qing,Zhong Bo-Hua,Xie Jian-Wei

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Drug Discovery,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/s12272-013-0300-6.pdf

Reference19 articles.

1. Balzarini, J., A. Holy, J. Jindrich, L. Naesens, R. Snoeck, D. Schols, and E. De Clercq. 1993. Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine. Antimicrobial Agents and Chemotherapy 37: 332–338.

2. Benzaria, S., H. Pelicano, R. Johnson, G. Maury, J.L. Imbach, A.M. Aubertin, G. Obert, and G. Gosselin. 1996. Synthesis, in vitro antiviral evaluation, and stability studies of bis(S-acyl-2-thioethyl) ester derivatives of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA) as potential PMEA prodrugs with improved oral bioavailability. Journal of Medicinal Chemistry 39: 4958–4965.

3. Cundy, K.C., J.P. Shaw, and W.A. Lee. 1994. Oral, subcutaneous, and intramuscular bioavailabilities of the antiviral nucleotide analog 9-(2-phosphonylmethoxyethyl)adenine in cynomolgus monkeys. Antimicrobial Agents and Chemotherapy 38: 365–368.

4. Erion, M.D., K.R. Reddy, S.H. Boyer, M.C. Matelich, J. Gomez-Galeno, R.H. Lemus, B.G. Ugarkar, T.J. Colby, J. Schanzer, and P.D. Van Poelje. 2004. Design, synthesis, and characterization of a series of cytochrome P(450) 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver. Journal of the American Chemical Society 126: 5154–5163.

5. Guan, R., and H.F. Lui. 2011. Treatment of hepatitis B in decompensated liver cirrhosis. International Journal of Hepatology 2011: 918017.

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis of polyfluoroalkylphosphorylated dihydroquinolines and dihydroisoquinolines decorated with N-acylethenyl substituents by the reaction of bis(polyfluoroalkyl)phosphonates with electron-deficient acetylenes and quinolines;Journal of Fluorine Chemistry;2023-08

2. Reaction of polyfluoroalkyl dichlorophosphites with propargyl alcohol: synthesis and isomerization of polyfluoroalkyl di(2-propynyl) phosphites;Russian Chemical Bulletin;2021-11

3. Free Radical Hydrophosphorylation of Fluoroalkyl Vinyl Ethers: Synthesis of Fluoroalkyl Phosphonates;Russian Journal of General Chemistry;2020-04

4. Catalyst- and Solvent-Free Synthesis of α-Amino Polyfluoroalkylphosphonates from Bis(fluoroalkyl) Phosphonates and Aldimines;Synthesis;2020-02-13

5. Phosphonate prodrugs: an overview and recent advances;Future Medicinal Chemistry;2019-07