Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate

Author:

Jurkowska Halina,Roman Heather B.,Hirschberger Lawrence L.,Sasakura Kiyoshi,Nagano Tetsuo,Hanaoka Kenjiro,Krijt Jakub,Stipanuk Martha H.

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Clinical Biochemistry,Biochemistry

Reference56 articles.

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2. Ang A, Konigstorfer A, Giles G, Bhatia M (2012) Measuring free tissue sulfide. Adv Biol Chem 2:360–365

3. Bella DL, Stipanuk MH (1995) Effects of protein, methionine, or chloride on acid-base balance and on cysteine catabolism. Am J Physiol 269:E910–E917

4. Bradley H, Gough A, Sokhi RS, Hassell A, Waring R, Emery P (1994) Sulfate metabolism is abnormal in patients with rheumatoid arthritis. Confirmation by in vivo biochemical findings. J Rheumatol 21:1192–1196

5. Brait M, Ling S, Nagpal JK, Chang X, Park HL, Lee J, Okamura J, Yamashita K, Sidransky D, Kim MS (2012) Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers. PLoS One 7(9):e44951

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